Coordinate linkage of HIV evolution reveals regions of immunological vulnerability

Proceedings of the National Academy of Sciences , Vol. 108, No. 28. , pp. 11530-11535, doi:10.1073/pnas.1105315108 Cellular immune control of HIV is mediated, in part, by induction of single amino acid mutations that reduce viral fitness, but compensatory mutations limit this effect.

http://www.citeulike.org/user/vvoorr/article/9443909